For decades, the health of women and gender diverse people has been under-researched, leading to disparities in health outcomes, gaps in access to care and too many instances of mis- and under-diagnosis. The National Women’s Health Research Initiative (NWHRI), led by the Canadian Institutes of Health Research (CIHR) and supported by Women and Gender Equality Canada, has been working to change that, with a focus on evidence-based solutions that will directly improve women’s and gender diverse people’s access to and experience within the health care system.